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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

Neural stem cells, which exhibit self-renewal and multipotentiality, are generated in early embryonic brains and maintained throughout the lifespan. The mechanisms of their generation and maintenance are largely unknown. Here, we show that neural stem cells are generated independent of RBP-Jκ, a key...

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מידע ביבליוגרפי
Main Authors: Hitoshi, Seiji, Alexson, Tania, Tropepe, Vincent, Donoviel, Dorit, Elia, Andrew J., Nye, Jeffrey S., Conlon, Ronald A., Mak, Tak W., Bernstein, Alan, van der Kooy, Derek
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2002
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC186324/
https://ncbi.nlm.nih.gov/pubmed/11937492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.975202
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