Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Deficiency Results in Exencephaly and Is Required for Apoptosis within the Developing CNS

Tumor necrosis factor receptor-associated factors (TRAFs) are adaptor proteins important in mediating intracellular signaling. We report here that targeted deletion of traf6 greatly increases the frequency of failure of neural tube closure and exencephaly in traf6 (−/−) mice. The penetrance of this...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Lomaga, Mark A., Henderson, Jeffrey T., Elia, Andrew J., Robertson, Jennifer, Noyce, Ryan S., Yeh, Wen-Chen, Mak, Tak W.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2000
Fag:
ARTICLE
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772765/
https://ncbi.nlm.nih.gov/pubmed/11007897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-19-07384.2000
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker