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Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate
Pancreatic endocrine cells expand rapidly during embryogenesis by neogenesis and proliferation, but during adulthood, islet cells have a very slow turnover. Disruption of murine retinoblastoma tumor suppressor protein (Rb) in mature pancreatic β-cells has a limited effect on cell proliferation. Here...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767525/ https://ncbi.nlm.nih.gov/pubmed/23946427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303386110 |
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