Regulation of protein synthesis by the heme-regulated eIF2α kinase: relevance to anemias

od Chen, Jane-Jane
Izdano 2007

Translational Control by Heme-Regulated eIF2α Kinase during Erythropoiesis

od Chen, Jane-Jane
Izdano 2014

Stress-enhanced translation of γ-globin mRNA

od Chen, Jane-Jane
Izdano 2014

HRI stress signaling and HbF production

od Chen, Jane-Jane
Izdano u Blood (2020)

Stressing HbF synthesis: role of translation?

od Chen, Jane-Jane, Perrine, Susan
Izdano 2013

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies

od Chen, Jane-Jane, Zhang, Shuping
Izdano u Blood (2019)

Translation Initiation Control by Heme-Regulated Eukaryotic Initiation Factor 2α Kinase in Erythroid Cells under Cytoplasmic Stresses

od Lu, Linrong, Han, An-Ping, Chen, Jane-Jane
Izdano 2001

Heme-regulated eIF2α kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and β-thalassemia

od Han, An-Ping, Fleming, Mark D., Chen, Jane-Jane
Izdano 2005

Hepatic Heme-Regulated Inhibitor (HRI) Eukaryotic Initiation Factor 2α Kinase: A Protagonist of Heme-Mediated Translational Control of CYP2B Enzymes and a Modulator of Basal Endopl...

od Acharya, Poulomi, Chen, Jane-Jane, Correia, Maria Almira
Izdano 2010

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development

od Harding, Heather P., Zhang, Yuhong, Scheuner, Donalyn, Chen, Jane-Jane, Kaufman, Randal J., Ron, David
Izdano 2009

HRI coordinates translation by eIF2αP and mTORC1 to mitigate ineffective erythropoiesis in mice during iron deficiency

od Zhang, Shuping, Macias-Garcia, Alejandra, Velazquez, Jason, Paltrinieri, Elena, Kaufman, Randal J., Chen, Jane-Jane
Izdano u Blood (2018)

Deficiency of heme-regulated eIF2α kinase decreases hepcidin expression and splenic iron in HFE(−/−) mice

od Liu, Sijin, Suragani, Rajasekhar N.V.S., Han, Anping, Zhao, Wanting, Andrews, Nancy C., Chen, Jane-Jane
Izdano 2008

Phosphorylation of Eukaryotic Initiation Factor 2 by Heme-Regulated Inhibitor Kinase-Related Protein Kinases in Schizosaccharomyces pombe Is Important for Resistance to Environment...

od Zhan, Ke, Vattem, Krishna M., Bauer, Bettina N., Dever, Thomas E., Chen, Jane-Jane, Wek, Ronald C.
Izdano 2002

The function of heme-regulated eIF2α kinase in murine iron homeostasis and macrophage maturation

od Liu, Sijin, Suragani, Rajasekhar N.V.S., Wang, Fudi, Han, Anping, Zhao, Wanting, Andrews, Nancy C., Chen, Jane-Jane
Izdano 2007

Haem-regulated eIF2α kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency

od Liu, Sijin, Bhattacharya, Sanchita, Han, Anping, Suragani, Rajasekhar N. V. S., Zhao, Wanting, Fry, Rebecca C., Chen, Jane-Jane
Izdano u Br J Haematol (2008)

Expression of the Eukaryotic Translation Initiation Factors 4E and 2α in Non-Hodgkin’s Lymphomas

od Wang, Songtao, Rosenwald, Igor B., Hutzler, Michael J., Pihan, German A., Savas, Lou, Chen, Jane-Jane, Woda, Bruce A.
Izdano 1999

Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis

od Suragani, Rajasekhar N. V. S., Zachariah, Roshini S., Velazquez, Jason G., Liu, Sijin, Sun, Chiao-Wang, Townes, Tim M., Chen, Jane-Jane
Izdano 2012

HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis

od Zhang, Shuping, Macias-Garcia, Alejandra, Ulirsch, Jacob C, Velazquez, Jason, Butty, Vincent L, Levine, Stuart S, Sankaran, Vijay G, Chen, Jane-Jane
Izdano u eLife (2019)

Heme-regulated eIF2α kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency

od Han, An-Ping, Yu, Channing, Lu, Linrong, Fujiwara, Yuko, Browne, Carol, Chin, Gregory, Fleming, Mark, Leboulch, Philippe, Orkin, Stuart H., Chen, Jane-Jane
Izdano 2001

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

od Mukherjee, Tapas, Ramaglia, Valeria, Abdel-Nour, Mena, Bianchi, Athanasia A., Tsalikis, Jessica, Chau, Hien N., Kalia, Suneil K., Kalia, Lorraine V., Chen, Jane-Jane, Arnoult, Damien, Gommerman, Jennifer L., Philpott, Dana J., Girardin, Stephen E.
Izdano u J Biol Chem (2020)