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Translation Initiation Control by Heme-Regulated Eukaryotic Initiation Factor 2α Kinase in Erythroid Cells under Cytoplasmic Stresses

Cytoplasmic stresses, including heat shock, osmotic stress, and oxidative stress, cause rapid inhibition of protein synthesis in cells through phosphorylation of eukaryotic initiation factor 2α (eIF2α) by eIF2α kinases. We have investigated the role of heme-regulated inhibitor (HRI), a heme-regulate...

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Bibliografske podrobnosti
Main Authors: Lu, Linrong, Han, An-Ping, Chen, Jane-Jane
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC99965/
https://ncbi.nlm.nih.gov/pubmed/11689689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.7971-7980.2001
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