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Translation Initiation Control by Heme-Regulated Eukaryotic Initiation Factor 2α Kinase in Erythroid Cells under Cytoplasmic Stresses

Cytoplasmic stresses, including heat shock, osmotic stress, and oxidative stress, cause rapid inhibition of protein synthesis in cells through phosphorylation of eukaryotic initiation factor 2α (eIF2α) by eIF2α kinases. We have investigated the role of heme-regulated inhibitor (HRI), a heme-regulate...

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Detalhes bibliográficos
Main Authors: Lu, Linrong, Han, An-Ping, Chen, Jane-Jane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99965/
https://ncbi.nlm.nih.gov/pubmed/11689689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.7971-7980.2001
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