Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 α-Subunit Kinase, PEK, Involved in Translational Control

In response to various environmental stresses, eukaryotic cells down-regulate protein synthesis by phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF-2α). In mammals, the phosphorylation was shown to be carried out by eIF-2α kinases PKR and HRI. We report the identif...

Full description

Saved in:
Bibliographic Details
Main Authors: Shi, Yuguang, Vattem, Krishna M., Sood, Ruchira, An, Jie, Liang, Jingdong, Stramm, Lawrence, Wek, Ronald C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109330/
https://ncbi.nlm.nih.gov/pubmed/9819435
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items