Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 α-Subunit Kinase, PEK, Involved in Translational Control

In response to various environmental stresses, eukaryotic cells down-regulate protein synthesis by phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF-2α). In mammals, the phosphorylation was shown to be carried out by eIF-2α kinases PKR and HRI. We report the identif...

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Detalhes bibliográficos
Main Authors: Shi, Yuguang, Vattem, Krishna M., Sood, Ruchira, An, Jie, Liang, Jingdong, Stramm, Lawrence, Wek, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109330/
https://ncbi.nlm.nih.gov/pubmed/9819435
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