Yüklüyor......
HRI coordinates translation by eIF2αP and mTORC1 to mitigate ineffective erythropoiesis in mice during iron deficiency
Iron deficiency (ID) anemia is a prevalent disease, yet molecular mechanisms by which iron and heme regulate erythropoiesis are not completely understood. Heme-regulated eIF2α kinase (HRI) is a key hemoprotein in erythroid precursors that sense intracellular heme concentrations to balance globin syn...
Kaydedildi:
| Yayımlandı: | Blood |
|---|---|
| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2018
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790126/ https://ncbi.nlm.nih.gov/pubmed/29101239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-799908 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|