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Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies
As essential components of hemoglobin, iron and heme play central roles in terminal erythropoiesis. The impairment of this process in iron/heme deficiency results in microcytic hypochromic anemia, the most prevalent anemia globally. Heme-regulated eIF2α kinase, also known as heme-regulated inhibitor...
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| Publié dans: | Blood |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856985/ https://ncbi.nlm.nih.gov/pubmed/31554636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001915 |
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