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Regulation of protein synthesis by the heme-regulated eIF2α kinase: relevance to anemias
During erythroid differentiation and maturation, it is critical that the 3 components of hemoglobin, α-globin, β-globin, and heme, are made in proper stoichiometry to form stable hemoglobin. Heme-regulated translation mediated by the heme-regulated inhibitor kinase (HRI) provides one major mechanism...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852217/ https://ncbi.nlm.nih.gov/pubmed/17110456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-041830 |
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