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Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies

As essential components of hemoglobin, iron and heme play central roles in terminal erythropoiesis. The impairment of this process in iron/heme deficiency results in microcytic hypochromic anemia, the most prevalent anemia globally. Heme-regulated eIF2α kinase, also known as heme-regulated inhibitor...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Chen, Jane-Jane, Zhang, Shuping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856985/
https://ncbi.nlm.nih.gov/pubmed/31554636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001915
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