Protein-Folding Homeostasis in the Endoplasmic Reticulum and Nutritional Regulation

le Ron, David, Harding, Heather P.
Foilsithe 2012

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

le Lu, Phoebe D., Harding, Heather P., Ron, David
Foilsithe 2004

Uncoupling Proteostasis and Development in Vitro with a Small Molecule Inhibitor of the Pancreatic Endoplasmic Reticulum Kinase, PERK

le Harding, Heather P., Zyryanova, Alisa F., Ron, David
Foilsithe 2012

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

le Lin, Wensheng, Harding, Heather P., Ron, David, Popko, Brian
Foilsithe 2005

Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

le Novoa, Isabel, Zeng, Huiqing, Harding, Heather P., Ron, David
Foilsithe 2001

Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers

le Ordóñez, Adriana, Harding, Heather P., Marciniak, Stefan J., Ron, David
Foilsithe in Cell Rep (2021)

De-phosphorylation of translation initiation factor 2α (eIF2α) enhances glucose tolerance and attenuates hepato-steatosis in mice

le Oyadomari, Seiichi, Harding, Heather P., Zhang, Yuhong, Oyadomari, Miho, Ron, David
Foilsithe 2008

Ubiquitin-Like Protein 5 Positively Regulates Chaperone Gene Expression in the Mitochondrial Unfolded Protein Response

le Benedetti, Cristina, Haynes, Cole M., Yang, Yun, Harding, Heather P., Ron, David
Foilsithe 2006

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

le Zito, Ester, Chin, King-Tung, Blais, Jaime, Harding, Heather P., Ron, David
Foilsithe 2010

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

le Zito, Ester, Chin, King-Tung, Blais, Jaime, Harding, Heather P., Ron, David
Foilsithe 2010

Stress-induced gene expression requires programmed recovery from translational repression

le Novoa, Isabel, Zhang, Yuhong, Zeng, Huiqing, Jungreis, Rivka, Harding, Heather P., Ron, David
Foilsithe 2003

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK

le Marciniak, Stefan J., Garcia-Bonilla, Lidia, Hu, Junjie, Harding, Heather P., Ron, David
Foilsithe 2006

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

le Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A.
Foilsithe 2007

Inhibition of a constitutive translation initiation factor 2α phosphatase, CReP, promotes survival of stressed cells

le Jousse, Céline, Oyadomari, Seiichi, Novoa, Isabel, Lu, Phoebe, Zhang, Yuhong, Harding, Heather P., Ron, David
Foilsithe 2003

Enhanced Integrated Stress Response Promotes Myelinating Oligodendrocyte Survival in Response to Interferon-γ

le Lin, Wensheng, Kunkler, Phillip E., Harding, Heather P., Ron, David, Kraig, Richard P., Popko, Brian
Foilsithe 2008

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development

le Harding, Heather P., Zhang, Yuhong, Scheuner, Donalyn, Chen, Jane-Jane, Kaufman, Randal J., Ron, David
Foilsithe 2009

PERK Activation Preserves the Viability and Function of Remyelinating Oligodendrocytes in Immune-Mediated Demyelinating Diseases

le Lin, Yifeng, Huang, Guangcun, Jamison, Stephanie, Li, Jin, Harding, Heather P., Ron, David, Lin, Wensheng
Foilsithe 2014

Mutations in a translation initiation factor identify target of a memory-enhancing compound

le Sekine, Yusuke, Zyryanova, Alisa, Crespillo-Casado, Ana, Fischer, Peter M., Harding, Heather P., Ron, David
Foilsithe in Science (2015)

Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells

le Sekine, Yusuke, Zyryanova, Alisa, Crespillo-Casado, Ana, Amin-Wetzel, Niko, Harding, Heather P., Ron, David
Foilsithe in PLoS One (2016)

Dual role of the integrated stress response in medulloblastoma tumorigenesis

le Stone, Sarrabeth, Ho, Yeung, Li, Xiting, Jamison, Stephanie, Harding, Heather P., Ron, David, Lin, Wensheng
Foilsithe in Oncotarget (2016)