A DRUG-BASED CELLULAR ASSAY (DBCA) FOR STUDYING CYTOTOXIC AND CYTOPROTECTIVE ACTIVITIES OF THE PRION PROTEIN: A PRACTICAL GUIDE

Por Massignan, Tania, Biasini, Emiliano, Harris, David A.
Publicado em 2010

Ion channels induced by the prion protein: Mediators of neurotoxicity

Por Solomon, Isaac H, Biasini, Emiliano, Harris, David A
Publicado em 2012

PRION PROTEIN AT THE CROSSROADS OF PHYSIOLOGY AND DISEASE

Por Biasini, Emiliano, Turnbaugh, Jessie, Unterberger, Ursula, Harris, David A.
Publicado em 2011

The Compelling Demand for an Effective PrP(C)-Directed Therapy against Prion Diseases

Por Astolfi, Andrea, Spagnolli, Giovanni, Biasini, Emiliano, Barreca, Maria Letizia
Publicado no ACS Med Chem Lett (2020)

GFP-TAGGED MUTANT PRION PROTEIN FORMS INTRA-AXONAL AGGREGATES IN TRANSGENIC MICE

Por Medrano, Andrea Z., Barmada, Sami J., Biasini, Emiliano, Harris, David A.
Publicado em 2008

Aggregated, Wild-Type Prion Protein Causes Neurological Dysfunction and Synaptic Abnormalities

Por Chiesa, Roberto, Piccardo, Pedro, Biasini, Emiliano, Ghetti, Bernardino, Harris, David A.
Publicado em 2008

Pharmacological Agents Targeting the Cellular Prion Protein

Por Barreca, Maria Letizia, Iraci, Nunzio, Biggi, Silvia, Cecchetti, Violetta, Biasini, Emiliano
Publicado no Pathogens (2018)

The N-Terminal, Polybasic Region Is Critical for Prion Protein Neuroprotective Activity

Por Turnbaugh, Jessie A., Westergard, Laura, Unterberger, Ursula, Biasini, Emiliano, Harris, David A.
Publicado em 2011

The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells

Por Nyeste, Antal, Stincardini, Claudia, Bencsura, Petra, Cerovic, Milica, Biasini, Emiliano, Welker, Ervin
Publicado no Sci Rep (2016)

Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in...

Por Sempou, Emily, Biasini, Emiliano, Pinzón-Olejua, Alejandro, Harris, David A., Málaga-Trillo, Edward
Publicado no Mol Neurodegener (2016)

All-atom simulation of the HET-s prion replication

Por Terruzzi, Luca, Spagnolli, Giovanni, Boldrini, Alberto, Requena, Jesús R., Biasini, Emiliano, Faccioli, Pietro
Publicado no PLoS Comput Biol (2020)

Immunopurification of Pathological Prion Protein Aggregates

Por Biasini, Emiliano, Tapella, Laura, Mantovani, Susanna, Stravalaci, Matteo, Gobbi, Marco, Harris, David A., Chiesa, Roberto
Publicado em 2009

An N-terminal Polybasic Domain and Cell Surface Localization Are Required for Mutant Prion Protein Toxicity

Por Solomon, Isaac H., Khatri, Natasha, Biasini, Emiliano, Massignan, Tania, Huettner, James E., Harris, David A.
Publicado em 2011

Modeling PrP(Sc) Generation Through Deformed Templating

Por Spagnolli, Giovanni, Rigoli, Marta, Novi Inverardi, Giovanni, Codeseira, Yaiza B., Biasini, Emiliano, Requena, Jesús R.
Publicado no Front Bioeng Biotechnol (2020)

A Novel, Drug-based, Cellular Assay for the Activity of Neurotoxic Mutants of the Prion Protein

Por Massignan, Tania, Stewart, Richard S., Biasini, Emiliano, Solomon, Isaac H., Bonetto, Valentina, Chiesa, Roberto, Harris, David A.
Publicado em 2010

The Toxicity of a Mutant Prion Protein Is Cell-Autonomous, and Can Be Suppressed by Wild-Type Prion Protein on Adjacent Cells

Por Biasini, Emiliano, Turnbaugh, Jessie A., Massignan, Tania, Veglianese, Pietro, Forloni, Gianluigi, Bonetto, Valentina, Chiesa, Roberto, Harris, David A.
Publicado em 2012

Full atomistic model of prion structure and conversion

Por Spagnolli, Giovanni, Rigoli, Marta, Orioli, Simone, Sevillano, Alejandro M., Faccioli, Pietro, Wille, Holger, Biasini, Emiliano, Requena, Jesús R.
Publicado no PLoS Pathog (2019)

Mutant Prion Protein Expression Is Associated with an Alteration of the Rab GDP Dissociation Inhibitor α (GDI)/Rab11 Pathway

Por Massignan, Tania, Biasini, Emiliano, Lauranzano, Eliana, Veglianese, Pietro, Pignataro, Mauro, Fioriti, Luana, Harris, David A., Salmona, Mario, Chiesa, Roberto, Bonetto, Valentina
Publicado em 2010

Role of Lipid Rafts and GM1 in the Segregation and Processing of Prion Protein

Por Botto, Laura, Cunati, Diana, Coco, Silvia, Sesana, Silvia, Bulbarelli, Alessandra, Biasini, Emiliano, Colombo, Laura, Negro, Alessandro, Chiesa, Roberto, Masserini, Massimo, Palestini, Paola
Publicado em 2014

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans

Por Yin, Shaoman, Pham, Nancy, Yu, Shuiliang, Li, Chaoyang, Wong, Poki, Chang, Binggong, Kang, Shin-Chung, Biasini, Emiliano, Tien, Po, Harris, David A., Sy, Man-Sun
Publicado em 2007