A DRUG-BASED CELLULAR ASSAY (DBCA) FOR STUDYING CYTOTOXIC AND CYTOPROTECTIVE ACTIVITIES OF THE PRION PROTEIN: A PRACTICAL GUIDE

par Massignan, Tania, Biasini, Emiliano, Harris, David A.
Publié 2010

Ion channels induced by the prion protein: Mediators of neurotoxicity

par Solomon, Isaac H, Biasini, Emiliano, Harris, David A
Publié 2012

PRION PROTEIN AT THE CROSSROADS OF PHYSIOLOGY AND DISEASE

par Biasini, Emiliano, Turnbaugh, Jessie, Unterberger, Ursula, Harris, David A.
Publié 2011

The Compelling Demand for an Effective PrP(C)-Directed Therapy against Prion Diseases

par Astolfi, Andrea, Spagnolli, Giovanni, Biasini, Emiliano, Barreca, Maria Letizia
Publié dans ACS Med Chem Lett (2020)

GFP-TAGGED MUTANT PRION PROTEIN FORMS INTRA-AXONAL AGGREGATES IN TRANSGENIC MICE

par Medrano, Andrea Z., Barmada, Sami J., Biasini, Emiliano, Harris, David A.
Publié 2008

Aggregated, Wild-Type Prion Protein Causes Neurological Dysfunction and Synaptic Abnormalities

par Chiesa, Roberto, Piccardo, Pedro, Biasini, Emiliano, Ghetti, Bernardino, Harris, David A.
Publié 2008

Pharmacological Agents Targeting the Cellular Prion Protein

par Barreca, Maria Letizia, Iraci, Nunzio, Biggi, Silvia, Cecchetti, Violetta, Biasini, Emiliano
Publié dans Pathogens (2018)

The N-Terminal, Polybasic Region Is Critical for Prion Protein Neuroprotective Activity

par Turnbaugh, Jessie A., Westergard, Laura, Unterberger, Ursula, Biasini, Emiliano, Harris, David A.
Publié 2011

The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells

par Nyeste, Antal, Stincardini, Claudia, Bencsura, Petra, Cerovic, Milica, Biasini, Emiliano, Welker, Ervin
Publié dans Sci Rep (2016)

Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in...

par Sempou, Emily, Biasini, Emiliano, Pinzón-Olejua, Alejandro, Harris, David A., Málaga-Trillo, Edward
Publié dans Mol Neurodegener (2016)

All-atom simulation of the HET-s prion replication

par Terruzzi, Luca, Spagnolli, Giovanni, Boldrini, Alberto, Requena, Jesús R., Biasini, Emiliano, Faccioli, Pietro
Publié dans PLoS Comput Biol (2020)

Immunopurification of Pathological Prion Protein Aggregates

par Biasini, Emiliano, Tapella, Laura, Mantovani, Susanna, Stravalaci, Matteo, Gobbi, Marco, Harris, David A., Chiesa, Roberto
Publié 2009

An N-terminal Polybasic Domain and Cell Surface Localization Are Required for Mutant Prion Protein Toxicity

par Solomon, Isaac H., Khatri, Natasha, Biasini, Emiliano, Massignan, Tania, Huettner, James E., Harris, David A.
Publié 2011

Modeling PrP(Sc) Generation Through Deformed Templating

par Spagnolli, Giovanni, Rigoli, Marta, Novi Inverardi, Giovanni, Codeseira, Yaiza B., Biasini, Emiliano, Requena, Jesús R.
Publié dans Front Bioeng Biotechnol (2020)

A Novel, Drug-based, Cellular Assay for the Activity of Neurotoxic Mutants of the Prion Protein

par Massignan, Tania, Stewart, Richard S., Biasini, Emiliano, Solomon, Isaac H., Bonetto, Valentina, Chiesa, Roberto, Harris, David A.
Publié 2010

The Toxicity of a Mutant Prion Protein Is Cell-Autonomous, and Can Be Suppressed by Wild-Type Prion Protein on Adjacent Cells

par Biasini, Emiliano, Turnbaugh, Jessie A., Massignan, Tania, Veglianese, Pietro, Forloni, Gianluigi, Bonetto, Valentina, Chiesa, Roberto, Harris, David A.
Publié 2012

Full atomistic model of prion structure and conversion

par Spagnolli, Giovanni, Rigoli, Marta, Orioli, Simone, Sevillano, Alejandro M., Faccioli, Pietro, Wille, Holger, Biasini, Emiliano, Requena, Jesús R.
Publié dans PLoS Pathog (2019)

Mutant Prion Protein Expression Is Associated with an Alteration of the Rab GDP Dissociation Inhibitor α (GDI)/Rab11 Pathway

par Massignan, Tania, Biasini, Emiliano, Lauranzano, Eliana, Veglianese, Pietro, Pignataro, Mauro, Fioriti, Luana, Harris, David A., Salmona, Mario, Chiesa, Roberto, Bonetto, Valentina
Publié 2010

Role of Lipid Rafts and GM1 in the Segregation and Processing of Prion Protein

par Botto, Laura, Cunati, Diana, Coco, Silvia, Sesana, Silvia, Bulbarelli, Alessandra, Biasini, Emiliano, Colombo, Laura, Negro, Alessandro, Chiesa, Roberto, Masserini, Massimo, Palestini, Paola
Publié 2014

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans

par Yin, Shaoman, Pham, Nancy, Yu, Shuiliang, Li, Chaoyang, Wong, Poki, Chang, Binggong, Kang, Shin-Chung, Biasini, Emiliano, Tien, Po, Harris, David A., Sy, Man-Sun
Publié 2007