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The N-Terminal, Polybasic Region Is Critical for Prion Protein Neuroprotective Activity
Several lines of evidence suggest that the normal form of the prion protein, PrP(C), exerts a neuroprotective activity against cellular stress or toxicity. One of the clearest examples of such activity is the ability of wild-type PrP(C) to suppress the spontaneous neurodegenerative phenotype of tran...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183058/ https://ncbi.nlm.nih.gov/pubmed/21980526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025675 |
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