Llwytho...
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo
BACKGROUND: Prions and amyloid-β (Aβ) oligomers trigger neurodegeneration by hijacking a poorly understood cellular signal mediated by the prion protein (PrP) at the plasma membrane. In early zebrafish embryos, PrP-1-dependent signals control cell-cell adhesion via a tyrosine phosphorylation-depende...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Neurodegener |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748561/ https://ncbi.nlm.nih.gov/pubmed/26860872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0076-5 |
| Tagiau: |
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