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PrPs: Proteins with a purpose: Lessons from the zebrafish

The best-known attribute of the prion protein (PrP) is its tendency to misfold into a rogue isoform. Much less understood is how this misfolded isoform causes deadly brain illnesses. Neurodegeneration in prion disease is often seen as a consequence of abnormal PrP function yet, amazingly little is k...

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Detalhes bibliográficos
Main Authors: Málaga-Trillo, Edward, Sempou, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802776/
https://ncbi.nlm.nih.gov/pubmed/19786844
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