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Uncontrolled SFK-mediated protein trafficking in prion and Alzheimer's disease
Prions and Amyloid beta (Aβ) peptides induce synaptic damage via complex mechanisms that include the pathological alteration of intracellular signaling cascades. The host-encoded cellular prion protein (PrP(C)) acts as a high-affinity cell surface receptor for both toxic species and it can modulate...
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| Publicado en: | Prion |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5105932/ https://ncbi.nlm.nih.gov/pubmed/27649856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2016.1221873 |
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