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Uncontrolled SFK-mediated protein trafficking in prion and Alzheimer's disease

Prions and Amyloid beta (Aβ) peptides induce synaptic damage via complex mechanisms that include the pathological alteration of intracellular signaling cascades. The host-encoded cellular prion protein (PrP(C)) acts as a high-affinity cell surface receptor for both toxic species and it can modulate...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Málaga-Trillo, Edward, Ochs, Katharina
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105932/
https://ncbi.nlm.nih.gov/pubmed/27649856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2016.1221873
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