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Cellular prion protein and Alzheimer disease: Link to oligomeric amyloid-β and neuronal cell death
Soluble oligomeric amyloid-β (Aβ) has been suggested to impair synaptic and neuronal function, leading to neurodegeneration that is clinically observed as the memory and cognitive dysfunction characteristic of Alzheimer disease, while the precise mechanism(s) whereby oligomeric Aβ causes neurotoxici...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609115/ https://ncbi.nlm.nih.gov/pubmed/23154635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.22848 |
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