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β-amyloid oligomers and cellular prion protein in Alzheimer's disease

Prefibrillar oligomers of the β-amyloid peptide (Aβ) are recognized as potential mediators of Alzheimer's disease (AD) pathophysiology. Deficits in synaptic function, neurotoxicity, and the progression of AD have all been linked to the oligomeric Aβ assemblies rather than to Aβ monomers or to a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gunther, Erik C., Strittmatter, Stephen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846635/
https://ncbi.nlm.nih.gov/pubmed/19960174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0568-7
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