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Cellular Prion Protein as a Receptor for Amyloid-β Oligomers in Alzheimer’s Disease
Soluble oligomers of amyloid-beta (Aβo) are implicated by biochemical and genetic evidence as a trigger for Alzheimer’s disease (AD) pathophysiology. A key step is Aβo interaction with the neuronal surface to initiate a cascade of altered signal transduction leading to synaptic dysfunction and damag...
Shranjeno v:
| izdano v: | Biochem Biophys Res Commun |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5303667/ https://ncbi.nlm.nih.gov/pubmed/27639648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.09.062 |
| Oznake: |
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