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Cellular Prion Protein Mediates the Toxicity of β-Amyloid Oligomers: Implications for Alzheimer Disease
Alzheimer disease (AD) is the most common cause of age-related dementia, affecting more than 25 million people worldwide. The accumulation of insoluble β-amyloid (Aβ) plaques in the brain has long been considered central to the pathogenesis of AD. However, recent evidence suggests that soluble oligo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849161/ https://ncbi.nlm.nih.gov/pubmed/19901162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2009.223 |
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