Загрузка...

Cellular Prion Protein Mediates the Toxicity of β-Amyloid Oligomers: Implications for Alzheimer Disease

Alzheimer disease (AD) is the most common cause of age-related dementia, affecting more than 25 million people worldwide. The accumulation of insoluble β-amyloid (Aβ) plaques in the brain has long been considered central to the pathogenesis of AD. However, recent evidence suggests that soluble oligo...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Nygaard, Haakon B., Strittmatter, Stephen M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849161/
https://ncbi.nlm.nih.gov/pubmed/19901162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2009.223
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!