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Src- and confinement-dependent FAK activation causes E-cadherin relaxation and β-catenin activity
In epithelia, E-cadherin cytoplasmic tail is under cytoskeleton-generated tension via a link that contains β-catenin. A cotranscription factor, β-catenin, is also active in morphogenetic processes associated with epithelial-to-mesenchymal transition. β-Catenin signaling appears mechanically inducibl...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5839785/ https://ncbi.nlm.nih.gov/pubmed/29311227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706013 |
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