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Tac-β1 Inhibits FAK Activation and Src Signaling

The binding of integrins to extracellular matrix triggers signals that promote cell spreading. We previously demonstrated that expression of the integrin β1 cytoplasmic domain in the context of a chimeric transmembrane receptor with the Tac subunit of the interleukin-2 receptor (Tac-β1) inhibits cel...

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Detalles Bibliográficos
Main Authors: Berrier, Allison L., Jones, Christopher W., LaFlamme, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587174/
https://ncbi.nlm.nih.gov/pubmed/18198129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.01.034
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