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Ion channels induced by the prion protein: Mediators of neurotoxicity

Prion diseases comprise a group of rapidly progressive and invariably fatal neurodegenerative disorders for which there are no effective treatments. While conversion of the cellular prion protein (PrP(C)) to a β-sheet rich isoform (PrP(Sc)) is known to be a critical event in propagation of infectiou...

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Detalhes bibliográficos
Main Authors: Solomon, Isaac H, Biasini, Emiliano, Harris, David A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338964/
https://ncbi.nlm.nih.gov/pubmed/22453177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.6.1.18627
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