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Prion Neurotoxicity: Insights from Prion Protein Mutants

The chemical nature of prions and the mechanism by which they propagate are now reasonably well understood. In contrast, much less is known about the identity of the toxic prion protein (PrP) species that are responsible for neuronal death, and the cellular pathways that these forms activate. In add...

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Detalhes bibliográficos
Publicado no:Curr Issues Mol Biol
Main Authors: Solomon, Isaac H., Schepker, Jessie A., Harris, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821541/
https://ncbi.nlm.nih.gov/pubmed/19767650
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