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A Nine Amino Acid Domain Is Essential for Mutant Prion Protein Toxicity

Transgenic mice expressing prion protein (PrP) molecules with several different internal deletions display spontaneous neurodegenerative phenotypes that can be dose-dependently suppressed by coexpression of wild-type PrP. Each of these deletions, including the largest one (Δ32–134), retains 9 aa imm...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Westergard, Laura, Turnbaugh, Jessie A., Harris, David A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Neuroscience 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227396/
https://ncbi.nlm.nih.gov/pubmed/21957261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1243-11.2011
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