Modeling PrP(Sc) Generation Through Deformed Templating

Deformed templating is the process by which self-replicating protein conformations with a given cross-β folding pattern can seed formation of an alternative self-replicating state with different cross-β folding pattern. In particular, uninfectious but propagative PrP amyloid can transform into a bon...

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Bibliographic Details
Published in:Front Bioeng Biotechnol
Main Authors: Spagnolli, Giovanni, Rigoli, Marta, Novi Inverardi, Giovanni, Codeseira, Yaiza B., Biasini, Emiliano, Requena, Jesús R.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Bioengineering and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573312/
https://ncbi.nlm.nih.gov/pubmed/33123520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.590501
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