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Full atomistic model of prion structure and conversion
Prions are unusual protein assemblies that propagate their conformationally-encoded information in absence of nucleic acids. The first prion identified, the scrapie isoform (PrP(Sc)) of the cellular prion protein (PrP(C)), caused epidemic and epizootic episodes [1]. Most aggregates of other misfoldi...
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| Pubblicato in: | PLoS Pathog |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6622554/ https://ncbi.nlm.nih.gov/pubmed/31295325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007864 |
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