The Structure of Human Prions: From Biology to Structural Models — Considerations and Pitfalls

Por Acevedo-Morantes, Claudia Y., Wille, Holger
Publicado em 2014

Elucidating the structure of an infectious protein

Por Zweckstetter, Markus, Requena, Jesús R., Wille, Holger
Publicado no PLoS Pathog (2017)

Conformational Diversity of Wild-type Tau Fibrils Specified by Templated Conformation Change

Por Frost, Bess, Ollesch, Julian, Wille, Holger, Diamond, Marc I.
Publicado em 2009

Evidence for assembly of prions with left-handed β-helices into trimers

Por Govaerts, Cédric, Wille, Holger, Prusiner, Stanley B., Cohen, Fred E.
Publicado em 2004

Colloid Formation by Drugs in Simulated Intestinal Fluid

Por Doak, Allison K., Wille, Holger, Prusiner, Stanley B., Shoichet, Brian K.
Publicado em 2010

Self-Assembling Small Molecules Form Nanofibrils That Bind Procaspase-3 to Promote Activation

Por Zorn, Julie A., Wille, Holger, Wolan, Dennis W., Wells, James A.
Publicado em 2011

Evolutionary Descent of Prion Genes from the ZIP Family of Metal Ion Transporters

Por Schmitt-Ulms, Gerold, Ehsani, Sepehr, Watts, Joel C., Westaway, David, Wille, Holger
Publicado em 2009

Molecular Modeling of the Misfolded Insulin Subunit and Amyloid Fibril

Por Choi, Jay H., May, Barnaby C.H., Wille, Holger, Cohen, Fred E.
Publicado em 2009

A Neuronal Culture System to Detect Prion Synaptotoxicity

Por Fang, Cheng, Imberdis, Thibaut, Garza, Maria Carmen, Wille, Holger, Harris, David A.
Publicado no PLoS Pathog (2016)

Degradation of Fungal Prion HET-s(218-289) Induces Formation of a Generic Amyloid Fold

Por Wan, William, Wille, Holger, Stöhr, Jan, Baxa, Ulrich, Prusiner, Stanley B., Stubbs, Gerald
Publicado em 2012

Plasma Membrane Invaginations Containing Clusters of Full-length PrP(Sc) are an Early Form of Prion-associated Neuropathology in vivo

Por Godsave, Susan F., Wille, Holger, Pierson, Jason, Prusiner, Stanley B., Peters, Peter J.
Publicado em 2013

Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation

Por Breid, Sara, Bernis, Maria E., Babila, Julius T., Garza, Maria C., Wille, Holger, Tamgüney, Gültekin
Publicado no J Virol (2016)

Identification of Discrete Classes of Endosome-derived Small Vesicles as a Major Cellular Pool for Recycling Membrane Proteins

Por Lim, Seong-Nam, Bonzelius, Frank, Low, Seng Hui, Wille, Holger, Weimbs, Thomas, Herman, Gary A
Publicado em 2001

Electron crystallography of the scrapie prion protein complexed with heavy metals

Por Wille, Holger, Govaerts, Cédric, Borovinskiy, Alexander, Latawiec, Diane, Downing, Kenneth H., Cohen, Fred E., Prusiner, Stanley B.
Publicado em 2007

Mechanism of Scrapie Prion Precipitation with Phosphotungstate Anions

Por Levine, Dana J., Stöhr, Jan, Falese, Lillian E., Ollesch, Julian, Wille, Holger, Prusiner, Stanley B., Long, Jeffrey R.
Publicado no ACS Chem Biol (2014)

Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein

Por Wille, Holger, Shanmugam, Maheswaran, Murugesu, Muralee, Ollesch, Julian, Stubbs, Gerald, Long, Jeffrey R., Safar, Jiri G., Prusiner, Stanley B.
Publicado em 2009

Design and construction of diverse mammalian prion strains

Por Colby, David W., Giles, Kurt, Legname, Giuseppe, Wille, Holger, Baskakov, Ilia V., DeArmond, Stephen J., Prusiner, Stanley B.
Publicado em 2009

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains

Por Duque Velásquez, Camilo, Kim, Chiye, Herbst, Allen, Daude, Nathalie, Garza, Maria Carmen, Wille, Holger, Aiken, Judd, McKenzie, Debbie
Publicado no J Virol (2015)

Structural studies of the scrapie prion protein by electron crystallography

Por Wille, Holger, Michelitsch, Melissa D., Guénebaut, Vincent, Supattapone, Surachai, Serban, Ana, Cohen, Fred E., Agard, David A., Prusiner, Stanley B.
Publicado em 2002

Protease-Resistant Prions Selectively Decrease Shadoo Protein

Por Watts, Joel C., Stöhr, Jan, Bhardwaj, Sumita, Wille, Holger, Oehler, Abby, DeArmond, Stephen J., Giles, Kurt, Prusiner, Stanley B.
Publicado em 2011