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The Evolutionary unZIPping of a Dimerization Motif—A Comparison of ZIP and PrP Architectures
The cellular prion protein, notorious for its causative role in a range of fatal neurodegenerative diseases, evolved from a Zrt-/Irt-like Protein (ZIP) zinc transporter approximately 500 million years ago. Whilst atomic structures for recombinant prion protein (PrP) from various species have been av...
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| Publicado no: | Pathogens |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5874730/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens7010004 |
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