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A DRUG-BASED CELLULAR ASSAY (DBCA) FOR STUDYING CYTOTOXIC AND CYTOPROTECTIVE ACTIVITIES OF THE PRION PROTEIN: A PRACTICAL GUIDE

Although a great deal of progress has been made in elucidating the molecular identity of the infectious agent in prion diseases, the mechanisms by which prions kill neurons, and the role of the cellular prion protein (PrP(C)) in this process, remain enigmatic. A window into the normal function of Pr...

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Detalhes bibliográficos
Main Authors: Massignan, Tania, Biasini, Emiliano, Harris, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384733/
https://ncbi.nlm.nih.gov/pubmed/21115124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.11.005
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