An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein

Prion diseases are neurodegenerative conditions characterized by the conformational conversion of the cellular prion protein (PrP(C)), an endogenous membrane glycoprotein of uncertain function, into PrP(Sc), a pathological isoform that replicates by imposing its abnormal folding onto PrP(C) molecule...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stincardini, Claudia, Massignan, Tania, Biggi, Silvia, Elezgarai, Saioa R., Sangiovanni, Valeria, Vanni, Ilaria, Pancher, Michael, Adami, Valentina, Moreno, Jorge, Stravalaci, Matteo, Maietta, Giulia, Gobbi, Marco, Negro, Alessandro, Requena, Jesús R., Castilla, Joaquín, Nonno, Romolo, Biasini, Emiliano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546605/
https://ncbi.nlm.nih.gov/pubmed/28787011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182589
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados