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Immunopurification of Pathological Prion Protein Aggregates
BACKGROUND: Prion diseases are fatal neurodegenerative disorders that can arise sporadically, be genetically inherited or acquired through infection. The key event in these diseases is misfolding of the cellular prion protein (PrP(C)) into a pathogenic isoform that is rich in β-sheet structure. This...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773113/ https://ncbi.nlm.nih.gov/pubmed/19915706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007816 |
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