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The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers
15B3 is a monoclonal IgM antibody that selectively detects pathological aggregates of the prion protein (PrP). We report the unexpected finding that 15B3 also recognizes oligomeric but not monomeric forms of amyloid-β (Aβ)(42), an aggregating peptide implicated in the pathogenesis of Alzheimer’s dis...
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| 出版年: | J Alzheimers Dis |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
IOS Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5044783/ https://ncbi.nlm.nih.gov/pubmed/27392850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150882 |
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