Synchronized targeting of Notch and ERBB signaling suppresses melanoma tumor growth through inhibition of Notch1 and ERBB3

Por Zhang, Keman, Wong, Poki, Salvaggio, Christine, Salhi, Amel, Osman, Iman, Bedogni, Barbara
Publicado no J Invest Dermatol (2015)

Noncanonical Activation of Notch1 Protein by Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Controls Melanoma Cell Proliferation

Por Ma, Jun, Tang, Xiaoying, Wong, Poki, Jacobs, Barbara, Borden, Ernest C., Bedogni, Barbara
Publicado em 2014

A Notch1-neuregulin1 autocrine signaling loop contributes to melanoma growth

Por Zhang, Keman, Wong, Poki, Zhang, Lukun, Jacobs, Barbara, Borden, Ernest C., Aster, Jon C., Bedogni, Barbara
Publicado em 2012

Biochemical Fingerprints of Prion Infection: Accumulations of Aberrant Full-Length and N-Terminally Truncated PrP Species Are Common Features in Mouse Prion Disease

Por Pan, Tao, Wong, Poki, Chang, Binggong, Li, Chaoyang, Li, Ruliang, Kang, Shin-Chung, Wisniewski, Thomas, Sy, Man-Sun
Publicado em 2005

Ligand binding promotes prion protein aggregation – role of the octapeptide repeats

Por Yu, Shuiliang, Yin, Shaoman, Pham, Nancy, Wong, Poki, Kang, Shin-Chung, Petersen, Robert B., Li, Chaoyang, Sy, Man-Sun
Publicado em 2008

Normal cellular prion protein is a ligand of selectins: binding requires Le(X) but is inhibited by sLe(X)

Por Li, Chaoyang, Wong, Poki, Pan, Tao, Xiao, Fan, Yin, Shaoman, Chang, Binggong, Kang, Shin-Chung, Ironside, James, Sy, Man-Sun
Publicado em 2007

Aggregation of prion protein with insertion mutations is proportional to the number of inserts

Por Yu, Shuiliang, Yin, Shaoman, Li, Chaoyang, Wong, Poki, Chang, Binggong, Xiao, Fan, Kang, Shin-Chung, Yan, Huimin, Xiao, Gengfu, Tien, Po, Sy, Man-Sun
Publicado em 2007

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans

Por Yin, Shaoman, Pham, Nancy, Yu, Shuiliang, Li, Chaoyang, Wong, Poki, Chang, Binggong, Kang, Shin-Chung, Biasini, Emiliano, Tien, Po, Harris, David A., Sy, Man-Sun
Publicado em 2007

Test for Detection of Disease-Associated Prion Aggregate in the Blood of Infected but Asymptomatic Animals

Por Chang, Binggong, Cheng, Xin, Yin, Shaoman, Pan, Tao, Zhang, Hongtao, Wong, Poki, Kang, Shin-Chung, Xiao, Fan, Yan, Huimin, Li, Chaoyang, Wolfe, Lisa L., Miller, Michael W., Wisniewski, Thomas, Greene, Mark I., Sy, Man-Sun
Publicado em 2007

An Aggregation-Specific Enzyme-Linked Immunosorbent Assay: Detection of Conformational Differences between Recombinant PrP Protein Dimers and PrP(Sc) Aggregates

Por Pan, Tao, Chang, Binggong, Wong, Poki, Li, Chaoyang, Li, Ruliang, Kang, Shin-Chung, Robinson, John D., Thompsett, Andrew R., Tein, Po, Yin, Shaoman, Barnard, Geoff, McConnell, Ian, Brown, David R., Wisniewski, Thomas, Sy, Man-Sun
Publicado em 2005