Biochemical Fingerprints of Prion Infection: Accumulations of Aberrant Full-Length and N-Terminally Truncated PrP Species Are Common Features in Mouse Prion Disease

Infection with any one of three strains of mouse scrapie prion (PrP(Sc)), 139A, ME7, or 22L, results in the accumulation of two underglycosylated, full-length PrP species and an N-terminally truncated PrP species that are not detectable in uninfected animals. The levels of the N-terminally truncated...

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Detalhes bibliográficos
Main Authors: Pan, Tao, Wong, Poki, Chang, Binggong, Li, Chaoyang, Li, Ruliang, Kang, Shin-Chung, Wisniewski, Thomas, Sy, Man-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538529/
https://ncbi.nlm.nih.gov/pubmed/15613322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.934-943.2005
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