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Biochemical Fingerprints of Prion Infection: Accumulations of Aberrant Full-Length and N-Terminally Truncated PrP Species Are Common Features in Mouse Prion Disease

Infection with any one of three strains of mouse scrapie prion (PrP(Sc)), 139A, ME7, or 22L, results in the accumulation of two underglycosylated, full-length PrP species and an N-terminally truncated PrP species that are not detectable in uninfected animals. The levels of the N-terminally truncated...

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Détails bibliographiques
Auteurs principaux: Pan, Tao, Wong, Poki, Chang, Binggong, Li, Chaoyang, Li, Ruliang, Kang, Shin-Chung, Wisniewski, Thomas, Sy, Man-Sun
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC538529/
https://ncbi.nlm.nih.gov/pubmed/15613322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.934-943.2005
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