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Biochemical Fingerprints of Prion Infection: Accumulations of Aberrant Full-Length and N-Terminally Truncated PrP Species Are Common Features in Mouse Prion Disease
Infection with any one of three strains of mouse scrapie prion (PrP(Sc)), 139A, ME7, or 22L, results in the accumulation of two underglycosylated, full-length PrP species and an N-terminally truncated PrP species that are not detectable in uninfected animals. The levels of the N-terminally truncated...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538529/ https://ncbi.nlm.nih.gov/pubmed/15613322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.934-943.2005 |
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