Biological Effects and Use of PrP(Sc)- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions

The prion agent is the infectious particle causing spongiform encephalopathies in animals and humans and is thought to consist of an altered conformation (PrP(Sc)) of the normal and ubiquitous prion protein PrP(C). The interaction of the prion agent with the immune system, particularly the humoral i...

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Hlavní autoři: Petsch, Benjamin, Müller-Schiffmann, Andreas, Lehle, Anna, Zirdum, Elizabeta, Prikulis, Ingrid, Kuhn, Franziska, Raeber, Alex J., Ironside, James W., Korth, Carsten, Stitz, Lothar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126253/
https://ncbi.nlm.nih.gov/pubmed/21345946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02467-10
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