Biological Effects and Use of PrP(Sc)- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions

The prion agent is the infectious particle causing spongiform encephalopathies in animals and humans and is thought to consist of an altered conformation (PrP(Sc)) of the normal and ubiquitous prion protein PrP(C). The interaction of the prion agent with the immune system, particularly the humoral i...

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Main Authors: Petsch, Benjamin, Müller-Schiffmann, Andreas, Lehle, Anna, Zirdum, Elizabeta, Prikulis, Ingrid, Kuhn, Franziska, Raeber, Alex J., Ironside, James W., Korth, Carsten, Stitz, Lothar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126253/
https://ncbi.nlm.nih.gov/pubmed/21345946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02467-10
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