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Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions

Disease-related prion protein (PrP(Sc)), which is a structural isoform of the host-encoded cellular prion protein, is thought to be a causative agent of transmissible spongiform encephalopathies. However, the specific role of PrP(Sc) in prion pathogenesis and its relationship to infectivity remain c...

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Bibliografski detalji
Izdano u:Prion
Glavni autori: Miyazawa, Kohtaro, Okada, Hiroyuki, Masujin, Kentaro, Iwamaru, Yoshifumi, Yokoyama, Takashi
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964868/
https://ncbi.nlm.nih.gov/pubmed/26555211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1111507
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