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Heterogeneity of the Abnormal Prion Protein (PrP(Sc)) of the Chandler Scrapie Strain
The pathological prion protein, PrP(Sc), displays various sizes of aggregates. In this study, we investigated the conformation, aggregation stability and proteinase K (PK)-sensitivity of small and large PrP(Sc) aggregates of mouse-adapted prion strains. We showed that small PrP(Sc) aggregates, previ...
Guardat en:
| Publicat a: | Pathogens |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235706/ https://ncbi.nlm.nih.gov/pubmed/25436883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens2010092 |
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