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Heterogeneity of the Abnormal Prion Protein (PrP(Sc)) of the Chandler Scrapie Strain

The pathological prion protein, PrP(Sc), displays various sizes of aggregates. In this study, we investigated the conformation, aggregation stability and proteinase K (PK)-sensitivity of small and large PrP(Sc) aggregates of mouse-adapted prion strains. We showed that small PrP(Sc) aggregates, previ...

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Bibliografski detalji
Izdano u:Pathogens
Glavni autori: Kasai, Kazuo, Iwamaru, Yoshifumi, Masujin, Kentaro, Imamura, Morikazu, Mohri, Shirou, Yokoyama, Takashi
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235706/
https://ncbi.nlm.nih.gov/pubmed/25436883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens2010092
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