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Emergence of a novel bovine spongiform encephalopathy (BSE) prion from an atypical H-type BSE

The H-type of atypical bovine spongiform encephalopathy (H-BSE) was serially passaged in bovinized transgenic (TgBoPrP) mice. At the fourth passage, most challenged mice showed a typical H-BSE phenotype with incubation periods of 223 ± 7.8 days. However, a different phenotype of BSE prion with short...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Masujin, Kentaro, Okada, Hiroyuki, Miyazawa, Kohtaro, Matsuura, Yuichi, Imamura, Morikazu, Iwamaru, Yoshifumi, Murayama, Yuichi, Yokoyama, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780101/
https://ncbi.nlm.nih.gov/pubmed/26948374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22753
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