Characterization of prion protein (PrP)-derived peptides that discriminate full-length PrP(Sc) from PrP(C)

On our initial discovery that prion protein (PrP)-derived peptides were capable of capturing the pathogenic prion protein (PrP(Sc)), we have been interested in how these peptides interact with PrP(Sc). After screening peptides from the entire human PrP sequence, we found two peptides (PrP(19–30) and...

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Xehetasun bibliografikoak
Egile Nagusiak: Lau, Anthony L., Yam, Alice Y., Michelitsch, Melissa M. D., Wang, Xuemei, Gao, Carol, Goodson, Robert J., Shimizu, Robert, Timoteo, Gulliver, Hall, John, Medina-Selby, Angelica, Coit, Doris, McCoin, Colin, Phelps, Bruce, Wu, Ping, Hu, Celine, Chien, David, Peretz, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904418/
https://ncbi.nlm.nih.gov/pubmed/17601775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704260104
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