Characterization of prion protein (PrP)-derived peptides that discriminate full-length PrP(Sc) from PrP(C)

On our initial discovery that prion protein (PrP)-derived peptides were capable of capturing the pathogenic prion protein (PrP(Sc)), we have been interested in how these peptides interact with PrP(Sc). After screening peptides from the entire human PrP sequence, we found two peptides (PrP(19–30) and...

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Detalhes bibliográficos
Main Authors: Lau, Anthony L., Yam, Alice Y., Michelitsch, Melissa M. D., Wang, Xuemei, Gao, Carol, Goodson, Robert J., Shimizu, Robert, Timoteo, Gulliver, Hall, John, Medina-Selby, Angelica, Coit, Doris, McCoin, Colin, Phelps, Bruce, Wu, Ping, Hu, Celine, Chien, David, Peretz, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904418/
https://ncbi.nlm.nih.gov/pubmed/17601775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704260104
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