Characterization of prion protein (PrP)-derived peptides that discriminate full-length PrP(Sc) from PrP(C)

On our initial discovery that prion protein (PrP)-derived peptides were capable of capturing the pathogenic prion protein (PrP(Sc)), we have been interested in how these peptides interact with PrP(Sc). After screening peptides from the entire human PrP sequence, we found two peptides (PrP(19–30) and...

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Bibliographic Details
Main Authors: Lau, Anthony L., Yam, Alice Y., Michelitsch, Melissa M. D., Wang, Xuemei, Gao, Carol, Goodson, Robert J., Shimizu, Robert, Timoteo, Gulliver, Hall, John, Medina-Selby, Angelica, Coit, Doris, McCoin, Colin, Phelps, Bruce, Wu, Ping, Hu, Celine, Chien, David, Peretz, David
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904418/
https://ncbi.nlm.nih.gov/pubmed/17601775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704260104
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