Characterization of prion protein (PrP)-derived peptides that discriminate full-length PrP(Sc) from PrP(C)

On our initial discovery that prion protein (PrP)-derived peptides were capable of capturing the pathogenic prion protein (PrP(Sc)), we have been interested in how these peptides interact with PrP(Sc). After screening peptides from the entire human PrP sequence, we found two peptides (PrP(19–30) and...

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Bibliografski detalji
Glavni autori: Lau, Anthony L., Yam, Alice Y., Michelitsch, Melissa M. D., Wang, Xuemei, Gao, Carol, Goodson, Robert J., Shimizu, Robert, Timoteo, Gulliver, Hall, John, Medina-Selby, Angelica, Coit, Doris, McCoin, Colin, Phelps, Bruce, Wu, Ping, Hu, Celine, Chien, David, Peretz, David
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904418/
https://ncbi.nlm.nih.gov/pubmed/17601775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704260104
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