Characterization of prion protein (PrP)-derived peptides that discriminate full-length PrP(Sc) from PrP(C)

On our initial discovery that prion protein (PrP)-derived peptides were capable of capturing the pathogenic prion protein (PrP(Sc)), we have been interested in how these peptides interact with PrP(Sc). After screening peptides from the entire human PrP sequence, we found two peptides (PrP(19–30) and...

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Détails bibliographiques
Auteurs principaux: Lau, Anthony L., Yam, Alice Y., Michelitsch, Melissa M. D., Wang, Xuemei, Gao, Carol, Goodson, Robert J., Shimizu, Robert, Timoteo, Gulliver, Hall, John, Medina-Selby, Angelica, Coit, Doris, McCoin, Colin, Phelps, Bruce, Wu, Ping, Hu, Celine, Chien, David, Peretz, David
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904418/
https://ncbi.nlm.nih.gov/pubmed/17601775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704260104
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