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Biochemical Fingerprints of Prion Infection: Accumulations of Aberrant Full-Length and N-Terminally Truncated PrP Species Are Common Features in Mouse Prion Disease

Infection with any one of three strains of mouse scrapie prion (PrP(Sc)), 139A, ME7, or 22L, results in the accumulation of two underglycosylated, full-length PrP species and an N-terminally truncated PrP species that are not detectable in uninfected animals. The levels of the N-terminally truncated...

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Dettagli Bibliografici
Autori principali: Pan, Tao, Wong, Poki, Chang, Binggong, Li, Chaoyang, Li, Ruliang, Kang, Shin-Chung, Wisniewski, Thomas, Sy, Man-Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC538529/
https://ncbi.nlm.nih.gov/pubmed/15613322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.934-943.2005
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