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Normal cellular prion protein is a ligand of selectins: binding requires Le(X) but is inhibited by sLe(X)
The normal PrP(C) (cellular prion protein) contains sLe(X) [sialyl-Le(X) (Lewis X)] and Le(X). sLe(X) is a ligand of selectins. To examine whether PrP(C) is a ligand of selectins, we generated three human PrP(C)–Ig fusion proteins: one with Le(X), one with sLe(X), and the other with neither Le(X) no...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Portland Press Ltd.
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948967/ https://ncbi.nlm.nih.gov/pubmed/17497959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061857 |
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