A range of C∊3–C∊4 interdomain angles in IgE Fc accommodate binding to its receptor CD23

Por Dhaliwal, Balvinder, Pang, Marie O. Y., Yuan, Daopeng, Beavil, Andrew J., Sutton, Brian J.
Publicado em 2014

Thermal sensitivity and flexibility of the Cε3 domains in immunoglobulin E

Por Doré, Katy A., Davies, Anna M., Drinkwater, Nyssa, Beavil, Andrew J., McDonnell, James M., Sutton, Brian J.
Publicado no Biochim Biophys Acta (2017)

Attenuation of IgE Affinity for FcεRI Radically Reduces the Allergic Response in Vitro and in Vivo

Por Hunt, James, Bracher, Marguerite G., Shi, Jianguo, Fleury, Sébastien, Dombrowicz, David, Gould, Hannah J., Sutton, Brian J., Beavil, Andrew J.
Publicado em 2008

Identification of Contact Residues and Definition of the CAR-Binding Site of Adenovirus Type 5 Fiber Protein

Por Kirby, Ian, Davison, Elizabeth, Beavil, Andrew J., Soh, Cecilia P. C., Wickham, Thomas J., Roelvink, Peter W., Kovesdi, Imre, Sutton, Brian J., Santis, George
Publicado em 2000

Mutations in the DG Loop of Adenovirus Type 5 Fiber Knob Protein Abolish High-Affinity Binding to Its Cellular Receptor CAR

Por Kirby, Ian, Davison, Elizabeth, Beavil, Andrew J., Soh, Cecilia P. C., Wickham, Thomas J., Roelvink, Peter W., Kovesdi, Imre, Sutton, Brian J., Santis, George
Publicado em 1999

Ca(2+)-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E

Por Yuan, Daopeng, Keeble, Anthony H., Hibbert, Richard G., Fabiane, Stella, Gould, Hannah J., McDonnell, James M., Beavil, Andrew J., Sutton, Brian J., Dhaliwal, Balvinder
Publicado em 2013

IgE binds asymmetrically to its B cell receptor CD23

Por Dhaliwal, Balvinder, Pang, Marie O. Y., Keeble, Anthony H., James, Louisa K., Gould, Hannah J., McDonnell, James M., Sutton, Brian J., Beavil, Andrew J.
Publicado no Sci Rep (2017)

Activated Ezrin Promotes Cell Migration through Recruitment of the GEF Dbl to Lipid Rafts and Preferential Downstream Activation of Cdc42

Por Prag, Soren, Parsons, Maddy, Keppler, Melanie D., Ameer-Beg, Simon M., Barber, Paul, Hunt, James, Beavil, Andrew J., Calvert, Rosy, Arpin, Monique, Vojnovic, Borivoj, Ng, Tony
Publicado em 2007

Conformational plasticity at the IgE-binding site of the B-cell receptor CD23()

Por Dhaliwal, Balvinder, Pang, Marie O.Y., Yuan, Daopeng, Yahya, Norhakim, Fabiane, Stella M., McDonnell, James M., Gould, Hannah J., Beavil, Andrew J., Sutton, Brian J.
Publicado em 2013

A Fluorescent Biosensor Reveals Conformational Changes in Human Immunoglobulin E Fc: IMPLICATIONS FOR MECHANISMS OF RECEPTOR BINDING, INHIBITION, AND ALLERGEN RECOGNITION

Por Hunt, James, Keeble, Anthony H., Dale, Robert E., Corbett, Melissa K., Beavil, Rebecca L., Levitt, James, Swann, Marcus J., Suhling, Klaus, Ameer-Beg, Simon, Sutton, Brian J., Beavil, Andrew J.
Publicado em 2012

IgE Trimers Drive SPE-7 Cytokinergic Activity

Por Bax, Heather J., Bowen, Holly, Beavil, Rebecca L., Chung, Raymond, Ward, Malcolm, Davies, Anna M., Dodev, Tihomir S., McDonnell, James M., Beavil, Andrew J., Sutton, Brian J., Gould, Hannah J.
Publicado no Sci Rep (2017)

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI

Por Dhaliwal, Balvinder, Yuan, Daopeng, Pang, Marie O. Y., Henry, Alistair J., Cain, Katharine, Oxbrow, Amanda, Fabiane, Stella M., Beavil, Andrew J., McDonnell, James M., Gould, Hannah J., Sutton, Brian J.
Publicado em 2012

Soluble CD23 Controls IgE Synthesis and Homeostasis in Human B Cells

Por Cooper, Alison M., Hobson, Philip S., Jutton, Mark R., Kao, Michael W., Drung, Binia, Schmidt, Boris, Fear, David J., Beavil, Andrew J., McDonnell, James M., Sutton, Brian J., Gould, Hannah J.
Publicado em 2012

A tool kit for rapid cloning and expression of recombinant antibodies

Por Dodev, Tihomir S., Karagiannis, Panagiotis, Gilbert, Amy E., Josephs, Debra H., Bowen, Holly, James, Louisa K., Bax, Heather J., Beavil, Rebecca, Pang, Marie O., Gould, Hannah J., Karagiannis, Sophia N., Beavil, Andrew J.
Publicado em 2014

Mapping of the CD23 Binding Site on Immunoglobulin E (IgE) and Allosteric Control of the IgE-FcϵRI Interaction

Por Borthakur, Susmita, Hibbert, Richard G., Pang, Marie O. Y., Yahya, Norhakim, Bax, Heather J., Kao, Michael W., Cooper, Alison M., Beavil, Andrew J., Sutton, Brian J., Gould, Hannah J., McDonnell, James M.
Publicado em 2012

Human immunoglobulin E flexes between acutely bent and extended conformations

Por Drinkwater, Nyssa, Cossins, Ben, Keeble, Anthony H, Wright, Michael, Cain, Katharine, Hailu, Hanna, Oxbrow, Amanda, Delgado, Jean, Shuttleworth, Lindsay K, Kao, Michael W-P, McDonnell, James M, Beavil, Andrew J, Henry, Alistair J, Sutton, Brian J
Publicado em 2014

Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab

Por Davies, Anna M., Allan, Elizabeth G., Keeble, Anthony H., Delgado, Jean, Cossins, Benjamin P., Mitropoulou, Alkistis N., Pang, Marie O. Y., Ceska, Tom, Beavil, Andrew J., Craggs, Graham, Westwood, Marta, Henry, Alistair J., McDonnell, James M., Sutton, Brian J.
Publicado no J Biol Chem (2017)

Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells

Por Karagiannis, Panagiotis, Singer, Josef, Hunt, James, Gan, Samuel K. E., Rudman, Sarah M., Mechtcheriakova, Diana, Knittelfelder, Regina, Daniels, Tracy R., Hobson, Philip S., Beavil, Andrew J., Spicer, James, Nestle, Frank O., Penichet, Manuel L., Gould, Hannah J., Jensen-Jarolim, Erika, Karagiannis, Sophia N.
Publicado em 2008

Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

Por Ilieva, Kristina M., Fazekas-Singer, Judit, Achkova, Daniela Y., Dodev, Tihomir S., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Cheung, Anthony, Karagiannis, Panagiotis, Correa, Isabel, Figini, Mariangela, Marlow, Rebecca, Josephs, Debra H., Beavil, Andrew J., Maher, John, Spicer, James F., Jensen-Jarolim, Erika, Tutt, Andrew N., Karagiannis, Sophia N.
Publicado no Front Immunol (2017)

Monitoring the Systemic Human Memory B Cell Compartment of Melanoma Patients for Anti-Tumor IgG Antibodies

Por Gilbert, Amy E., Karagiannis, Panagiotis, Dodev, Tihomir, Koers, Alexander, Lacy, Katie, Josephs, Debra H., Takhar, Pooja, Geh, Jenny L. C., Healy, Ciaran, Harries, Mark, Acland, Katharine M., Rudman, Sarah M., Beavil, Rebecca L., Blower, Philip J., Beavil, Andrew J., Gould, Hannah J., Spicer, James, Nestle, Frank O., Karagiannis, Sophia N.
Publicado em 2011