SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling

nork Harburg, Gwyndolen, Compton, Jennifer, Liu, Wei, Iwai, Naomi, Zada, Shahrzad, Marlow, Rebecca, Strickland, Phyllis, Zeng, Yi Arial, Hinck, Lindsay
Argitaratua izan da Stem Cell Reports (2014)

Vascular Robo4 restricts proangiogenic VEGF signaling in breast

nork Marlow, Rebecca, Binnewies, Mikhail, Sorensen, Lise K., Monica, Stefanie D., Strickland, Phyllis, Forsberg, E. Camilla, Li, Dean Y., Hinck, Lindsay
Argitaratua 2010

Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation

nork Akhtar, Nasreen, Marlow, Rebecca, Lambert, Elise, Schatzmann, Franziska, Lowe, Emma T., Cheung, Julia, Katz, Elad, Li, Weiping, Wu, Chuanyue, Dedhar, Shoukat, Naylor, Matthew J., Streuli, Charles H.
Argitaratua 2009

SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

nork Marlow, Rebecca, Strickland, Phyllis, Lee, Ji Shin, Wu, Xinyan, PeBenito, Milana, Binnewies, Mikhail, Le, Elizabeth K., Moran, Angel, Macias, Hector, Cardiff, Robert D., Sukumar, Saraswati, Hinck, Lindsay
Argitaratua 2008

Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium

nork Honeth, Gabriella, Lombardi, Sara, Ginestier, Christophe, Hur, Minhee, Marlow, Rebecca, Buchupalli, Bharath, Shinomiya, Ireneusz, Gazinska, Patrycja, Bombelli, Silvia, Ramalingam, Vernie, Purushotham, Anand D, Pinder, Sarah E, Dontu, Gabriela
Argitaratua 2014

Ablation of β1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation

nork Naylor, Matthew J., Li, Na, Cheung, Julia, Lowe, Emma T., Lambert, Elise, Marlow, Rebecca, Wang, Pengbo, Schatzmann, Franziska, Wintermantel, Timothy, Schüetz, Günther, Clarke, Alan R., Mueller, Ulrich, Hynes, Nancy E., Streuli, Charles H.
Argitaratua 2005

Growth Hormone Is Secreted by Normal Breast Epithelium upon Progesterone Stimulation and Increases Proliferation of Stem/Progenitor Cells

nork Lombardi, Sara, Honeth, Gabriella, Ginestier, Christophe, Shinomiya, Ireneusz, Marlow, Rebecca, Buchupalli, Bharath, Gazinska, Patrycja, Brown, John, Catchpole, Steven, Liu, Suling, Barkan, Ariel, Wicha, Max, Purushotham, Anand, Burchell, Joy, Pinder, Sarah, Dontu, Gabriela
Argitaratua 2014

Models of Breast Morphogenesis Based on Localization of Stem Cells in the Developing Mammary Lobule

nork Honeth, Gabriella, Schiavinotto, Tommaso, Vaggi, Federico, Marlow, Rebecca, Kanno, Tokuwa, Shinomiya, Ireneusz, Lombardi, Sara, Buchupalli, Bharath, Graham, Rosalind, Gazinska, Patrycja, Ramalingam, Vernie, Burchell, Joy, Purushotham, Anand D., Pinder, Sarah E., Csikasz-Nagy, Attila, Dontu, Gabriela
Argitaratua izan da Stem Cell Reports (2015)

Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)

nork Hoffmann, Ricarda M., Mele, Silvia, Cheung, Anthony, Larcombe-Young, Daniel, Bucaite, Gintare, Sachouli, Eirini, Zlatareva, Iva, Morad, Hassan O. J., Marlow, Rebecca, McDonnell, James M., Figini, Mariangela, Lacy, Katie E., Tutt, Andrew J. N., Spicer, James F., Thurston, David E., Karagiannis, Sophia N., Crescioli, Silvia
Argitaratua izan da Sci Rep (2020)

Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

nork Ilieva, Kristina M., Fazekas-Singer, Judit, Achkova, Daniela Y., Dodev, Tihomir S., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Cheung, Anthony, Karagiannis, Panagiotis, Correa, Isabel, Figini, Mariangela, Marlow, Rebecca, Josephs, Debra H., Beavil, Andrew J., Maher, John, Spicer, James F., Jensen-Jarolim, Erika, Tutt, Andrew N., Karagiannis, Sophia N.
Argitaratua izan da Front Immunol (2017)

Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer

nork Patel, Nirmesh, Weekes, Daniel, Drosopoulos, Konstantinos, Gazinska, Patrycja, Noel, Elodie, Rashid, Mamun, Mirza, Hasan, Quist, Jelmar, Brasó-Maristany, Fara, Mathew, Sumi, Ferro, Riccardo, Pereira, Ana Mendes, Prince, Cynthia, Noor, Farzana, Francesch-Domenech, Erika, Marlow, Rebecca, de Rinaldis, Emanuele, Grigoriadis, Anita, Linardopoulos, Spiros, Marra, Pierfrancesco, Tutt, Andrew N. J.
Argitaratua izan da Nat Commun (2018)

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer

nork Evans, Rachel, Flores-Borja, Fabian, Nassiri, Sina, Miranda, Elena, Lawler, Katherine, Grigoriadis, Anita, Monypenny, James, Gillet, Cheryl, Owen, Julie, Gordon, Peter, Male, Victoria, Cheung, Anthony, Noor, Farzana, Barber, Paul, Marlow, Rebecca, Francesch-Domenech, Erika, Fruhwirth, Gilbert, Squadrito, Mario, Vojnovic, Borivoj, Tutt, Andrew, Festy, Frederic, De Palma, Michele, Ng, Tony
Argitaratua izan da Cell Rep (2019)

Exploiting TRIM37-driven centrosome dysfunction to kill breast cancer cells

nork Yeow, Zhong Y., Lambrus, Bramwell G., Marlow, Rebecca, Zhan, Kevin H., Durin, Mary-Anne, Evans, Lauren T., Scott, Phillip M., Phan, Thao, Park, Elizabeth, Ruiz, Lorena A., Moralli, Daniela, Knight, Eleanor G., Badder, Luned M., Novo, Daniela, Haider, Syed, Green, Catherine M., Tutt, Andrew NJ, Lord, Christopher J, Chapman, J. Ross, Holland, Andrew J.
Argitaratua izan da Nature (2020)

PARP inhibition enhances tumor cell–intrinsic immunity in ERCC1-deficient non–small cell lung cancer

nork Chabanon, Roman M., Muirhead, Gareth, Krastev, Dragomir B., Adam, Julien, Morel, Daphné, Garrido, Marlène, Lamb, Andrew, Hénon, Clémence, Dorvault, Nicolas, Rouanne, Mathieu, Marlow, Rebecca, Bajrami, Ilirjana, Cardeñosa, Marta Llorca, Konde, Asha, Besse, Benjamin, Ashworth, Alan, Pettitt, Stephen J., Haider, Syed, Marabelle, Aurélien, Tutt, Andrew N.J., Soria, Jean-Charles, Lord, Christopher J., Postel-Vinay, Sophie
Argitaratua izan da J Clin Invest (2019)

PIM1 kinase regulates cell death, tumor growth and chemotherapy response revealing a novel target in triple-negative breast cancer

nork Brasó-Maristany, Fara, Filosto, Simone, Catchpole, Steven, Marlow, Rebecca, Quist, Jelmar, Francesch-Domenech, Erika, Plumb, Darren A., Zakka, Leila, Gazinska, Patrycja, Liccardi, Gianmaria, Meier, Pascal, Gris-Oliver, Albert, Cheang, Maggie Chon U, Perdrix-Rosell, Anna, Shafat, Manar, Noël, Elodie, Patel, Nirmesh, McEachern, Kristen, Scaltriti, Maurizio, Castel, Pau, Noor, Farzana, Buus, Richard, Mathew, Sumi, Watkins, Johnathan, Serra, Violeta, Marra, Pierfrancesco, Grigoriadis, Anita, Tutt, Andrew N.
Argitaratua izan da Nat Med (2016)

Anti-Folate Receptor alpha–directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer

nork Cheung, Anthony, Opzoomer, James, Ilieva, Kristina M, Gazinska, Patrycja, Hoffmann, Ricarda M, Mirza, Hasan, Marlow, Rebecca, Francesch-Domenech, Erika, Fittall, Matthew, Dominguez Rodriguez, Diana, Clifford, Angela, Badder, Luned, Patel, Nirmesh, Mele, Silvia, Pellizzari, Giulia, Bax, Heather J, Crescioli, Silvia, Petranyi, Gyula, Larcombe-Young, Daniel, Josephs, Debra H, Canevari, Silvana, Figini, Mariangela, Pinder, Sarah, Nestle, Frank O, Gillett, Cheryl, Spicer, James F, Grigoriadis, Anita, Tutt, Andrew N J, Karagiannis, Sophia N
Argitaratua izan da Clin Cancer Res (2018)

E-cadherin/ROS1 inhibitor synthetic lethality in breast cancer

nork Bajrami, Ilirjana, Marlow, Rebecca, van de Ven, Marieke, Brough, Rachel, Pemberton, Helen N., Frankum, Jessica, Song, Fei Fei, Rafiq, Rumana, Konde, Asha, Krastev, Dragomir B., Menon, Malini, Campbell, James, Gulati, Aditi, Kumar, Rahul, Pettitt, Stephen J., Gurden, Mark D., Cardenosa, Marta Llorca, Chong, Irene, Gazinska, Patrycja, Wallberg, Fredrik, Sawyer, Elinor J., Martin, Lesley-Ann, Dowsett, Mitch, Linardopoulos, Spiros, Natrajan, Rachael, Ryan, Colm J., Derksen, Patrick W.B., Jonkers, Jos, Tutt, Andrew N.J., Ashworth, Alan, Lord, Christopher J.
Argitaratua izan da Cancer Discov (2018)

3D functional genomics screens identify CREBBP as a targetable driver in aggressive triple-negative breast cancer

nork Peck, Barrie, Bland, Philip, Mavrommati, Ioanna, Muirhead, Gareth, Cottom, Hannah, Wai, Patty T., Maguire, Sarah L., Barker, Holly E., Morrison, Eamonn, Kriplani, Divya, Yu, Lu, Gibson, Amy, Falgari, Giulia, Brennan, Keith, Farnie, Gillian, Buus, Richard, Marlow, Rebecca, Novo, Daniela, Knight, Eleanor, Guppy, Naomi, Kolarevic, Daniela, Susnjar, Snezana, Milijic, Natasa Medic, Naidoo, Kalnisha, Gazinska, Patrycja, Roxanis, Ioannis, Pancholi, Sunil, Martin, Lesley-Ann, Holgersen, Erle M, Cheang, Maggie C.U., Noor, Farzana, Postel-Vinay, Sophie, Quinn, Gerard, McDade, Simon, Krasny, Lukas, Huang, Paul, Daley, Frances, Wallberg, Fredrik, Choudhary, Jyoti S., Haider, Syed, Tutt, Andrew N., Natrajan, Rachael
Argitaratua izan da Cancer Res (2021)

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

nork Zatreanu, Diana, Robinson, Helen M. R., Alkhatib, Omar, Boursier, Marie, Finch, Harry, Geo, Lerin, Grande, Diego, Grinkevich, Vera, Heald, Robert A., Langdon, Sophie, Majithiya, Jayesh, McWhirter, Claire, Martin, Niall M. B., Moore, Shaun, Neves, Joana, Rajendra, Eeson, Ranzani, Marco, Schaedler, Theresia, Stockley, Martin, Wiggins, Kimberley, Brough, Rachel, Sridhar, Sandhya, Gulati, Aditi, Shao, Nan, Badder, Luned M., Novo, Daniela, Knight, Eleanor G., Marlow, Rebecca, Haider, Syed, Callen, Elsa, Hewitt, Graeme, Schimmel, Joost, Prevo, Remko, Alli, Christina, Ferdinand, Amanda, Bell, Cameron, Blencowe, Peter, Bot, Chris, Calder, Mathew, Charles, Mark, Curry, Jayne, Ekwuru, Tennyson, Ewings, Katherine, Krajewski, Wojciech, MacDonald, Ellen, McCarron, Hollie, Pang, Leon, Pedder, Chris, Rigoreau, Laurent, Swarbrick, Martin, Wheatley, Ed, Willis, Simon, Wong, Ai Ching, Nussenzweig, Andre, Tijsterman, Marcel, Tutt, Andrew, Boulton, Simon J., Higgins, Geoff S., Pettitt, Stephen J., Smith, Graeme C. M., Lord, Christopher J.
Argitaratua izan da Nat Commun (2021)