3D functional genomics screens identify CREBBP as a targetable driver in aggressive triple-negative breast cancer

Triple-negative breast cancers (TNBC) are resistant to standard of care chemotherapy and lack known targetable driver gene alterations. Identification of novel drivers could aid the discovery of new treatment strategies for this hard-to-treat patient population, yet studies using high-throughput and...

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Publicado no:Cancer Res
Principais autores: Peck, Barrie, Bland, Philip, Mavrommati, Ioanna, Muirhead, Gareth, Cottom, Hannah, Wai, Patty T., Maguire, Sarah L., Barker, Holly E., Morrison, Eamonn, Kriplani, Divya, Yu, Lu, Gibson, Amy, Falgari, Giulia, Brennan, Keith, Farnie, Gillian, Buus, Richard, Marlow, Rebecca, Novo, Daniela, Knight, Eleanor, Guppy, Naomi, Kolarevic, Daniela, Susnjar, Snezana, Milijic, Natasa Medic, Naidoo, Kalnisha, Gazinska, Patrycja, Roxanis, Ioannis, Pancholi, Sunil, Martin, Lesley-Ann, Holgersen, Erle M, Cheang, Maggie C.U., Noor, Farzana, Postel-Vinay, Sophie, Quinn, Gerard, McDade, Simon, Krasny, Lukas, Huang, Paul, Daley, Frances, Wallberg, Fredrik, Choudhary, Jyoti S., Haider, Syed, Tutt, Andrew N., Natrajan, Rachael
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611219/
https://ncbi.nlm.nih.gov/pubmed/33509944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1822
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