CREBBP mutations in relapsed acute lymphoblastic leukaemia

Relapsed acute lymphoblastic leukaemia (ALL) is a leading cause of death due to disease in young people, but the biologic determinants of treatment failure remain poorly understood. Recent genome-wide profiling of structural DNA alterations in ALL have identified multiple submicroscopic somatic muta...

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Main Authors: Mullighan, Charles G., Zhang, Jinghui, Kasper, Lawryn H., Lerach, Stephanie, Payne-Turner, Debbie, Phillips, Letha A., Heatley, Sue L., Holmfeldt, Linda, Collins-Underwood, J. Racquel, Ma, Jing, Buetow, Kenneth H., Pui, Ching-Hon, Baker, Sharyn D., Brindle, Paul K., Downing, James R.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076610/
https://ncbi.nlm.nih.gov/pubmed/21390130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09727
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