Systematic Review and Meta-analysis of Randomized Trials of Central Nervous System Directed Therapy for Childhood Acute Lymphoblastic Leukaemia

Treatment of the central nervous system (CNS) is an essential therapy component for childhood acute lymphoblastic leukaemia (ALL). Individual patient data from 47 trials addressing 16 CNS treatment comparisons were analyzed. Event-free survival (EFS) was similar for radiotherapy versus IT, and radio...

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Bibliographic Details
Main Authors: Richards, Sue, Pui, Ching-Hon, Gayon, Paul
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461084/
https://ncbi.nlm.nih.gov/pubmed/22693038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24228
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