Precision cancer therapy: profiting from tumor specific defects in the DNA damage tolerance system

od Buoninfante, Olimpia Alessandra, Pilzecker, Bas, Aslam, Muhammad Assad, Zavrakidis, Ioannis, van der Wiel, Rianne, van de Ven, Marieke, van den Berk, Paul C.M., Jacobs, Heinz
Izdano u Oncotarget (2018)

Extended longevity mechanisms in short-lived progeroid mice: identification of a preservative stress response associated with successful aging

od van de Ven, Marieke, Andressoo, Jaan-Olle, Holcomb, Valerie B., Hasty, Paul, Suh, Yousin, van Steeg, Harry, Garinis, George A., Hoeijmakers, Jan H.J., Mitchell, James R.
Izdano 2006

Inhibition of the replication stress response is a synthetic vulnerability in SCLC that acts synergistically in combination with cisplatin

od Nagel, Remco, Avelar, Ana Teresa, Aben, Nanne, Proost, Natalie, van de Ven, Marieke, van der Vliet, Jan, Cozijnsen, Miranda, de Vries, Hilda, Wessels, Lodewyk F.A., Berns, Anton
Izdano u Mol Cancer Ther (2019)

Radiosensitivity is an acquired vulnerability of PARPi-resistant BRCA1-deficient tumors

od Barazas, Marco, Gasparini, Alessia, Huang, Yike, Küçükosmanoğlu, Asli, Annunziato, Stefano, Bouwman, Peter, Sol, Wendy, Kersbergen, Ariena, Proost, Natalie, de Korte-Grimmerink, Renske, van de Ven, Marieke, Jonkers, Jos, Borst, Gerben R., Rottenberg, Sven
Izdano u Cancer Res (2018)

Congenital DNA repair deficiency results in protection against renal ischemia reperfusion injury in mice

od Susa, Denis, Mitchell, James R., Verweij, Marielle, van de Ven, Marieke, Roest, Henk, van den Engel, Sandra, Bajema, Ingeborg, Mangundap, Kirsten, IJzermans, Jan N. M., Hoeijmakers, Jan H. J., de Bruin, Ron W. F.
Izdano 2009

Adaptive Stress Response in Segmental Progeria Resembles Long-Lived Dwarfism and Calorie Restriction in Mice

od van de Ven, Marieke, Andressoo, Jaan-Olle, Holcomb, Valerie B, von Lindern, Marieke, Jong, Willeke M. C, Zeeuw, Chris I. De, Suh, Yousin, Hasty, Paul, Hoeijmakers, Jan H. J, van der Horst, Gijsbertus T. J, Mitchell, James R
Izdano 2006

Correction: Adaptive Stress Response in Segmental Progeria Resembles Long-Lived Dwarfism and Calorie Restriction in Mice

od van de Ven, Marieke, Andressoo, Jaan-Olle, Holcomb, Valerie B, von Lindern, Marieke, Jong, Willeke M. C, Zeeuw, Chris I. De, Suh, Yousin, Hasty, Paul, Hoeijmakers, Jan H. J, van der Horst, Gijsbertus T. J, Mitchell, James R
Izdano 2008

SLC1A3 contributes to L‐asparaginase resistance in solid tumors

od Sun, Jianhui, Nagel, Remco, Zaal, Esther A, Ugalde, Alejandro Piñeiro, Han, Ruiqi, Proost, Natalie, Song, Ji‐Ying, Pataskar, Abhijeet, Burylo, Artur, Fu, Haigen, Poelarends, Gerrit J, van de Ven, Marieke, van Tellingen, Olaf, Berkers, Celia R, Agami, Reuven
Izdano u EMBO J (2019)

Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice

od Mitchell, James R., Verweij, Marielle, Brand, Karl, van de Ven, Marieke, Goemaere, Natascha, van den Engel, Sandra, Chu, Timothy, Forrer, Flavio, Müller, Cristina, de Jong, Marion, van Ijcken, Wilfred, IJzermans, Jan N. M., Hoeijmakers, Jan H. J., de Bruin, Ron W. F.
Izdano 2009

Rescue of Progeria in Trichothiodystrophy by Homozygous Lethal Xpd Alleles

od Andressoo, Jaan-Olle, Jans, Judith, de Wit, Jan, Coin, Frederic, Hoogstraten, Deborah, van de Ven, Marieke, Toussaint, Wendy, Huijmans, Jan, Thio, H. Bing, van Leeuwen, Wibeke J, de Boer, Jan, Egly, Jean-Marc, Hoeijmakers, Jan H. J, van der Horst, Gijsbertus T. J, Mitchell, James R
Izdano 2006

Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland

od Annunziato, Stefano, Kas, Sjors M., Nethe, Micha, Yücel, Hatice, Del Bravo, Jessica, Pritchard, Colin, Bin Ali, Rahmen, van Gerwen, Bas, Siteur, Bjørn, Drenth, Anne Paulien, Schut, Eva, van de Ven, Marieke, Boelens, Mirjam C., Klarenbeek, Sjoerd, Huijbers, Ivo J., van Miltenburg, Martine H., Jonkers, Jos
Izdano u Genes Dev (2016)

Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy

od Widmer, Carmen A., Klebic, Ismar, Domanitskaya, Natalya, Decollogny, Morgane, Howald, Denise, Siffert, Myriam, Essers, Paul, Nowicka, Zuzanna, Stokar-Regenscheit, Nadine, van de Ven, Marieke, de Korte-Grimmerink, Renske, Galván, José A., Pritchard, Colin E.J., Huijbers, Ivo J., Fendler, Wojciech, Vens, Conchita, Rottenberg, Sven
Izdano u Cancer Res Commun (2022)

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

od Barazas, Marco, Annunziato, Stefano, Pettitt, Stephen J., de Krijger, Inge, Ghezraoui, Hind, Roobol, Stefan J., Lutz, Catrin, Frankum, Jessica, Song, Fei Fei, Brough, Rachel, Evers, Bastiaan, Gogola, Ewa, Bhin, Jinhyuk, van de Ven, Marieke, van Gent, Dik C., Jacobs, Jacqueline J.L., Chapman, Ross, Lord, Christopher J., Jonkers, Jos, Rottenberg, Sven
Izdano u Cell Rep (2018)

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer

od Annunziato, Stefano, de Ruiter, Julian R., Henneman, Linda, Brambillasca, Chiara S., Lutz, Catrin, Vaillant, François, Ferrante, Federica, Drenth, Anne Paulien, van der Burg, Eline, Siteur, Bjørn, van Gerwen, Bas, de Bruijn, Roebi, van Miltenburg, Martine H., Huijbers, Ivo J., van de Ven, Marieke, Visvader, Jane E., Lindeman, Geoffrey J., Wessels, Lodewyk F. A., Jonkers, Jos
Izdano u Nat Commun (2019)

In situ CRISPR‐Cas9 base editing for the development of genetically engineered mouse models of breast cancer

od Annunziato, Stefano, Lutz, Catrin, Henneman, Linda, Bhin, Jinhyuk, Wong, Kim, Siteur, Bjørn, van Gerwen, Bas, de Korte‐Grimmerink, Renske, Zafra, Maria Paz, Schatoff, Emma M, Drenth, Anne Paulien, van der Burg, Eline, Eijkman, Timo, Mukherjee, Siddhartha, Boroviak, Katharina, Wessels, Lodewyk FA, van de Ven, Marieke, Huijbers, Ivo J, Adams, David J, Dow, Lukas E, Jonkers, Jos
Izdano u EMBO J (2020)

A BRCA1 coiled-coil domain variant disrupting PALB2 interaction promotes the development of mammary tumors and confers a targetable defect in homologous recombination repair

od Pulver, Emilia M., Mukherjee, Chirantani, van de Kamp, Gerarda, Roobol, Stefan J., Rother, Magdalena B., van der Gulden, Hanneke, de Bruijn, Roebi, Lattanzio, Maria Valeria, van der Burg, Eline, Drenth, Anne Paulien, Verkaik, Nicole S., Hahn, Kerstin, Klarenbeek, Sjoerd, de Korte-Grimmerink, Renske, van de Ven, Marieke, Pritchard, Colin E.J., Huijbers, Ivo J., Xia, Bing, van Gent, Dik C., Essers, Jeroen, van Attikum, Haico, Chaudhuri, Arnab Ray, Bouwman, Peter, Jonkers, Jos
Izdano u Cancer Res (2021)

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

od Gogola, Ewa, Duarte, Alexandra A., de Ruiter, Julian R., Wiegant, Wouter W., Schmid, Jonas A., de Bruijn, Roebi, James, Dominic I., Llobet, Sergi Guerrero, Vis, Daniel J., Annunziato, Stefano, van den Broek, Bram, Barazas, Marco, Kersbergen, Ariena, van de Ven, Marieke, Tarsounas, Madalena, Ogilvie, Donald J., van Vugt, Marcel, Wessels, Lodewyk F.A., Bartkova, Jirina, Gromova, Irina, Andújar-Sánchez, Miguel, Bartek, Jiri, Lopes, Massimo, van Attikum, Haico, Borst, Piet, Jonkers, Jos, Rottenberg, Sven
Izdano u Cancer Cell (2019)

BRCA1(185delAG) tumors may acquire therapy resistance through expression of RING-less BRCA1

od Drost, Rinske, Dhillon, Kiranjit K., van der Gulden, Hanneke, van der Heijden, Ingrid, Brandsma, Inger, Cruz, Cristina, Chondronasiou, Dafni, Castroviejo-Bermejo, Marta, Boon, Ute, Schut, Eva, van der Burg, Eline, Wientjens, Ellen, Pieterse, Mark, Klijn, Christiaan, Klarenbeek, Sjoerd, Loayza-Puch, Fabricio, Elkon, Ran, van Deemter, Liesbeth, Rottenberg, Sven, van de Ven, Marieke, Dekkers, Dick H.W., Demmers, Jeroen A.A., van Gent, Dik C., Agami, Reuven, Balmaña, Judith, Serra, Violeta, Taniguchi, Toshiyasu, Bouwman, Peter, Jonkers, Jos
Izdano u J Clin Invest (2016)

E-cadherin/ROS1 inhibitor synthetic lethality in breast cancer

od Bajrami, Ilirjana, Marlow, Rebecca, van de Ven, Marieke, Brough, Rachel, Pemberton, Helen N., Frankum, Jessica, Song, Fei Fei, Rafiq, Rumana, Konde, Asha, Krastev, Dragomir B., Menon, Malini, Campbell, James, Gulati, Aditi, Kumar, Rahul, Pettitt, Stephen J., Gurden, Mark D., Cardenosa, Marta Llorca, Chong, Irene, Gazinska, Patrycja, Wallberg, Fredrik, Sawyer, Elinor J., Martin, Lesley-Ann, Dowsett, Mitch, Linardopoulos, Spiros, Natrajan, Rachael, Ryan, Colm J., Derksen, Patrick W.B., Jonkers, Jos, Tutt, Andrew N.J., Ashworth, Alan, Lord, Christopher J.
Izdano u Cancer Discov (2018)

Long‐term expanding human airway organoids for disease modeling

od Sachs, Norman, Papaspyropoulos, Angelos, Zomer‐van Ommen, Domenique D, Heo, Inha, Böttinger, Lena, Klay, Dymph, Weeber, Fleur, Huelsz‐Prince, Guizela, Iakobachvili, Nino, Amatngalim, Gimano D, de Ligt, Joep, van Hoeck, Arne, Proost, Natalie, Viveen, Marco C, Lyubimova, Anna, Teeven, Luc, Derakhshan, Sepideh, Korving, Jeroen, Begthel, Harry, Dekkers, Johanna F, Kumawat, Kuldeep, Ramos, Emilio, van Oosterhout, Matthijs FM, Offerhaus, G Johan, Wiener, Dominique J, Olimpio, Eduardo P, Dijkstra, Krijn K, Smit, Egbert F, van der Linden, Maarten, Jaksani, Sridevi, van de Ven, Marieke, Jonkers, Jos, Rios, Anne C, Voest, Emile E, van Moorsel, Coline HM, van der Ent, Cornelis K, Cuppen, Edwin, van Oudenaarden, Alexander, Coenjaerts, Frank E, Meyaard, Linde, Bont, Louis J, Peters, Peter J, Tans, Sander J, van Zon, Jeroen S, Boj, Sylvia F, Vries, Robert G, Beekman, Jeffrey M, Clevers, Hans
Izdano u EMBO J (2019)